Lee L. Swanström (USA-France)

Jie He (China)

Michio Hongo (Japan)


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Session 1


Sunday, September 3
8:00 – 10:00 am

Room 1



Neuro-physiology of the esophagus


Chairs: Sutep Gonlachanvit (Thailand) – Hans Gregersen (Denmark-China)

Discussant: Larry Miller (USA)


The Esophagus-brain-esophagus axis

  • Brain imaging methods and esophagus-brain axis.
  • How can brain source modeling advance our understanding of the esophagus-brain axis?
  • How can evoked brain potentials advance our understanding of the esophagus-brain axis?
  • What are the characteristics of esophageal afferents in humans? Donald O. Castell (USA)
  • Can efficacy of the esophagus be improved by neurophysiological means?
  • What are the compensatory neurophysiological mechanisms for impaired esophageal mucosal defense?
    C. Prakash Gyawali (USA)

Multimodal stimulation and sensitization

  • How do we best study mechano-sensitive afferents in humans and in animal experiments?
  • What does distension studies reveal about esophageal efficacy and neurophysiological mechanisms?
    Hans Gregersen (Denmark-China)
  • What are the effects of physical and chemical stimulation of the esophageal body on UES opening and relaxation in normal subjects, elderly or in relation to esophageal disease? Barry McMahon (Ireland)
  • Do compensatory neurophysiological mechanisms exist for impaired esophageal transport?
  • What are the differences in neurophysiological characteristics of the proximal and distal esophagus?
  • Stimulation of protective factors in saliva. Jerzy Sarosiek (USA)


The aging esophagus and diseases

  • Why is esophagus function impaired in elderly and which symptoms does the impairment cause?
    Yinglian Xiao (China)
  • What is the clinical impact of sensitization of esophageal afferents? Richard W. McCallum (USA)
  • What is the role of TRPV1 in reflux hypersensitivity?
  • How are swallowing and respiration coordinated in elderly and in pulmonary diseases?
    Sutep Gonlachanvit (Thailand) 




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