Lee L. Swanström (USA-France)

Jie He (China)

Michio Hongo (Japan)


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Session 12


Sunday, September 3
2:00 – 4:00 pm

Room 2



Role of immune system


Chair: Markus Möhler (Germany)

Discussant: Salah-Eddin Al-Batran (Germany)


Immunology part:

  • What is the role of innate immune system in esophageal cancer?
  • Can the role of adaptive immune system in esophageal cancer be specified?
  • Is there a role of Micro RNA in the immune response of esophageal cancer?
  • Overcoming tumor-mediated immunosuppression in esophageal adenocarcinoma.
  • Is there a role for the Immunoscore in esophageal cancer?

Pathology part:

  • Is there a specific immune response that drives metaplasia and cancer in the esophagus?
  • Is there a difference between East and WEST, North and South?
  • Is there a difference between Male and female?

Pathophysiology part:

  • Which animal reflux-inflammation models are there for BE and EAC? Ines Gockel (Germany)
  • Are there specific cytokines involved in metaplasia-dysplasia-cancer sequence of the esophagus?


Clinical part:

  • Are there compounds that enhance the immune response in esophageal cancer patients?
  • What are the signaling pathways that can be targeted with immunotherapies?
  • What is the current state of immunotherapy for esophageal cancer?






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