Lee L. Swanström (USA-France)

Jie He (China)

Michio Hongo (Japan)


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Session 2


Sunday, September 3
8:00 – 10:00 am

Room 3



Neuro-physiology of the esophagus


Chairs: Sutep Gonlachanvit (Thailand) – Hans Gregersen (Denmark-China)

Discussant: Larry Miller (USA)


The Esophagus-brain-esophagus axis

  • The brain-esophagus axis. Mark Fox (Switzerland)
  • How can evoked brain potentials advance our understanding of the esophagus-brain axis?
    Dag Arne Hoff (Norway)
  • What are the characteristics of esophageal afferents in humans? Donald O. Castell (USA)
  • What are the compensatory neurophysiological mechanisms for impaired esophageal mucosal defense?
    C. Prakash Gyawali (USA)

Multimodal stimulation and sensitization

  • How do we best study mechano-sensitive afferents in humans? Dag Arne Hoff (Norway)
  • What does distension and other types of stimulations studies reveal about esophageal efficacy and neurophysiological mechanisms? Hans Gregersen (Denmark-China)
  • What are the effects of physical and chemical stimulation of the esophageal body on UES opening and relaxation in normal subjects, elderly or in relation to esophageal disease? Barry McMahon (Ireland)
  • Do compensatory neurophysiological mechanisms exist for impaired esophageal transport?
  • Stimulation of protective factors in saliva. Jerzy Sarosiek (USA)


The aging esophagus and diseases

  • Why is esophagus function impaired in elderly and which symptoms does the impairment cause?
    Barry McMahon (Ireland)
  • What is the clinical impact of sensitization of esophageal afferents? Richard W. McCallum (USA)
  • What is the role of TRPV1 in reflux hypersensitivity?
  • How are swallowing and respiration coordinated in elderly and in pulmonary diseases?
    Sutep Gonlachanvit (Thailand) 




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