Symposium 1











Attenzione: apre in una nuova finestra.

1 Sunday, September 2, 8:00 – 9:45 am
The esophageal mucosa and submucosa
Chairs: R.H. Riddell (Toronto) – M. Upton (Seattle)

  • Which cells normally exist in the esophageal epithelium? What is their function? R.H. Riddell (Toronto)
  • What is the function and role of submucosal mucous glands under the esophageal squamous epithelium? J. Sarosiek (El Paso)
  • Are Dilated Intercellular Spaces (DIS) normal? H.H. Wang (Boston)
  • Why/when do DIS occur? H. El-Zimaity (Toronto)
  • Should GEJ biopsies be taken in patients with reflux in the absence of vible BE? J. Abrams (New York)
  • Do cells in the lamina propria reflect those in the epithelium? H.D. Appelman (Ann Arbor)
  • How are stem cells identified in the squamous esophagus? M. Upton (Seattle)
  • Can stem cells be identified in Barrett’s dysplasia? X. Sagaert (Leuven)
  • What proportion of esophageal stem cells are marrow derived? D. Jain (Yale)
  • What is the origin and significance of multilayered epithelium? M. Vieth (Bayreuth)

The duplicated muscularis mucosae and its implications

  • When/why does duplication of the muscularis mucasae happen? K. Takubo (Tokyo)
  • Are there always 2 layers in BE? – If not, how do we know when are we definitively in the submucosa? C. Streutker (Toronto)
  • What is the function of the muscularis mucosae? X. Sagaert (Leuven)
  • Is the metastasizing potential of early carcinoma dependant on extent of spread through the duplicated muscularis mucosae? S. Abraham (Houston)
  • Does the choice of Endoscopic therapy matter in patients with dysplasia or intramucosal carcinoma R.C. Fitzgerald (Cambridge)
    a)    For initial therapy?
    b)    For subsequent therapy