Medical College of Wisconsin
The Medical College of Wisconsin OESO-SEMPIRE Pilot Center, anchored in the Pepsin and Reflux Laboratory and led by Nikki Johnston, is internationally recognized for redefining reflux disease beyond acid. Our work established pepsin as a central mediator of epithelial injury, inflammation, and carcinogenesis across the aero-digestive tract, reshaping the conceptual framework of laryngopharyngeal reflux (LPR). Building on this foundation, we are the first group worldwide to advance a targeted LPR therapeutic into investigator-initiated Phase II clinical trials, focusing on pepsin inhibition for PPI-refractory disease. Our multidisciplinary team of laryngologists, ENT scientists, and speech-language pathologists collaborates across gastroenterology, pulmonology, and global partners to translate mechanistic discovery into first-in-class diagnostics and therapies.
Institution
Medical College of Wisconsin
Continent
City
Milwaukee
Country
United States
Clinical case discussions
| Time | Session |
|---|---|
|
16:00
18:00
|
|
|
02:00
04:00
|